Robert Yarchoan Selected Research

Acquired Immunodeficiency Syndrome (AIDS)

8/2021	HIV-associated malignancies at 40: much accomplished but much to do.
10/2017	A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency.
4/2015	Kaposi sarcoma-associated herpesvirus-associated malignancies: epidemiology, pathogenesis, and advances in treatment.
5/2011	Cancer burden in the HIV-infected population in the United States.
8/2010	Characterization of immune responses to capsid protein p24 of human immunodeficiency virus type 1 and implications for detection.
1/2010	Radiotherapy for patients with the human immunodeficiency virus: are special precautions necessary?
12/2007	Phase 2 study of pegylated liposomal doxorubicin in combination with interleukin-12 for AIDS-related Kaposi sarcoma.
1/2007	Treatment of AIDS-related Kaposi's sarcoma with interleukin-12: rationale and preliminary evidence of clinical activity.
7/2006	Acquired immunodeficiency syndrome-related malignancies in the era of highly active antiretroviral therapy.
6/2006	Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma.

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Robert Yarchoan Research Topics

Disease

37	Kaposi Sarcoma (Kaposi's Sarcoma) 03/2022 - 03/2002
33	Neoplasms (Cancer) 01/2022 - 01/2003
17	Infections 01/2021 - 03/2002
13	Acquired Immunodeficiency Syndrome (AIDS) 08/2021 - 06/2003
11	Primary Effusion Lymphoma 01/2022 - 03/2007
11	Castleman Disease (Castleman's Disease) 01/2022 - 03/2007
7	Hypoxia (Hypoxemia) 01/2017 - 06/2003
6	Lymphoma (Lymphomas) 01/2021 - 06/2003
6	Multi-centric Castleman's Disease 01/2021 - 12/2014
4	HIV Infections (HIV Infection) 03/2022 - 11/2006
4	Neutropenia 01/2019 - 06/2006
4	Virus Diseases (Viral Diseases) 12/2018 - 07/2011
3	COVID-19 01/2021 - 01/2020
3	Hypoalbuminemia 01/2019 - 08/2010
3	Hypertension (High Blood Pressure) 01/2019 - 07/2010
3	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2019 - 04/2010
3	Hyponatremia 12/2013 - 08/2010
2	Viremia 01/2022 - 12/2016
2	Thrombocytopenia (Thrombopenia) 01/2019 - 01/2017
2	Immune Reconstitution Inflammatory Syndrome 10/2018 - 04/2015
2	Prostatic Neoplasms (Prostate Cancer) 04/2012 - 07/2010
2	Fever (Fevers) 01/2012 - 08/2010
2	Cytopenia 01/2012 - 08/2010
2	Opportunistic Infections (Opportunistic Infection) 04/2010 - 07/2006
2	AIDS-related Kaposi sarcoma 12/2007 - 06/2006
2	AIDS-Related Lymphoma (Lymphoma, AIDS Related) 07/2006 - 08/2005
1	Breast Neoplasms (Breast Cancer) 01/2022
1	T-Cell Leukemia (Leukemia, T Cell) 01/2022
1	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2022
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2021
1	Drug-Related Side Effects and Adverse Reactions 10/2020
1	Oral Manifestations 01/2020
1	Hypothyroidism 09/2019
1	Pneumonia (Pneumonitis) 09/2019
1	Autoimmune Diseases (Autoimmune Disease) 09/2019
1	Exanthema (Rash) 09/2019
1	Hepatitis B 09/2019
1	Gastrointestinal Hemorrhage (Hematochezia) 01/2019
1	Brain Ischemia (Cerebral Ischemia) 01/2019
1	WHIM syndrome 12/2018
1	Epidermodysplasia Verruciformis 12/2018

Drug/Important Bio-Agent (IBA)

12	CytokinesIBA 01/2022 - 01/2012
8	pomalidomideIBA 03/2022 - 04/2014
7	MicroRNAs (MicroRNA)IBA 11/2018 - 03/2007
5	Pharmaceutical PreparationsIBA 01/2021 - 01/2003
5	Rituximab (Mabthera)FDA Link 11/2020 - 04/2010
5	Interleukin-6 (Interleukin 6)IBA 01/2019 - 08/2010
5	liposomal doxorubicin (Doxil)FDA Link 01/2019 - 01/2007
4	Antiviral Agents (Antivirals)IBA 01/2021 - 08/2005
4	AntigensIBA 08/2017 - 06/2010
4	Sorafenib (BAY 43-9006)FDA Link 01/2017 - 07/2010
3	pembrolizumabIBA 01/2022 - 09/2019
3	Bevacizumab (Avastin)FDA Link 01/2019 - 07/2010
3	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2012
3	Zidovudine (Retrovir)FDA LinkGeneric 09/2012 - 07/2007
3	Interleukin-12 (IL 12)IBA 12/2007 - 06/2006
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2021 - 08/2017
2	Circular RNAIBA 01/2021 - 12/2018
2	Peptide Hydrolases (Proteases)FDA Link 01/2021 - 01/2020
2	remdesivirIBA 01/2021 - 01/2020
2	LigandsIBA 10/2020 - 09/2019
2	Monoclonal AntibodiesIBA 10/2020 - 09/2012
2	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2017
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 12/2003
2	Transaminases (Aminotransferases)IBA 09/2019 - 06/2006
2	Interleukin-10 (Interleukin 10)IBA 01/2019 - 12/2013
2	InterleukinsIBA 01/2019 - 08/2010
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2018 - 03/2002
2	Lenalidomide (CC 5013)FDA Link 08/2017 - 04/2014
2	endothelial PAS domain-containing protein 1IBA 01/2017 - 06/2003
2	Messenger RNA (mRNA)IBA 01/2017 - 01/2015
2	C-Reactive ProteinIBA 12/2013 - 01/2012
2	Valganciclovir FDA Link 09/2012 - 06/2011
2	BilirubinIBA 04/2012 - 06/2006
2	Peptides (Polypeptides)IBA 08/2010 - 03/2010
2	AntibodiesIBA 08/2010 - 06/2010
1	abemaciclibIBA 01/2022
1	CyclinsIBA 01/2022
1	InterferonsIBA 01/2022
1	ribociclibIBA 01/2022
1	palbociclibIBA 01/2022
1	Interleukin-13IBA 01/2021
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2021
1	Methotrexate (Mexate)FDA LinkGeneric 11/2020
1	Immune Checkpoint InhibitorsIBA 10/2020
1	NucleotidesIBA 01/2020
1	indoleIBA 01/2020
1	tocilizumab (atlizumab)FDA Link 01/2020
1	EstersIBA 01/2020
1	Alanine Transaminase (SGPT)IBA 09/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019
1	Circular DNAIBA 12/2018
1	plerixafor FDA Link 12/2018

Therapy/Procedure

38	Therapeutics 01/2022 - 01/2003
6	Highly Active Antiretroviral Therapy (HAART) 12/2007 - 05/2002
3	Immunotherapy 10/2020 - 08/2017
3	Art Therapy 09/2019 - 12/2016
3	Lasers (Laser) 01/2006 - 01/2004
2	Drug Therapy (Chemotherapy) 01/2021 - 12/2007
1	Intravenous Administration 01/2022